FIG. 5.

Plp-CreER^T2 expression pattern in the cochlea and utricle. Representative confocal images of the organ of Corti from Plp-CreER^T2;Ai14 mice, induced with tamoxifen at P0 and P1. A Slice image taken at the HC layer with tdTomato expression (red) and HCs labeled by myosin VIIA (myo7a, green). B Slice image at the SC nuclear layer with tdTomato expression (red) and SC nuclei labeled by Hoechst (white). Scale bar, 20 μm. C Quantification of tdTomato⁺ cells expressed as a percentage of total cells by type. IPC inner pillar cells, OPC outer pillar cells, DC Deiters’ cells, IPhC inner phalangeal cells. D–G Representative confocal images of the utricle from Plp-CreER^T2; ROSA26^eYFP mice, induced with tamoxifen at P0 and P1. E–G Artificial slice images of HCs labeled by myosin VIIA (myo7A, red) and eYFP expression (green). Cre activity is expressed in both HCs (arrows) and SCs. Scale bars, 50 μm (D) and 20 μm (E–G).