FIG. 6.

Illustration of Cre efficiency using a low efficiency Cre and two reporter lines. A–C Representative confocal images of the organ of Corti of Prox1-CreER^T2;CAG^eGFP;ROSA26^lacZ mice, induced with tamoxifen at P0 and P1. Many cells expressed either GFP (green) (A) or lacZ (βgal antibody labeling in red) (B), while only two cells were both GFP⁺ and lacZ⁺ (arrows). Nuclei are labeled with Hoechst in white. Scale bar, 20 μm.