Atoh1-Cre |
Knock-in |
E13.5: vestibular sensory regions; E14.5: basal turn of the cochlea; P0: HCs and SCs in cochlea and vestibular organs |
Cochlear and vestibular HCs (90 %), cochlear SCs (60 %), utricle SCs (6 %), saccule SCs (15 %), cristae SCs (42 %) |
Yang et al. (2010a) |
Not commercially available |
Atoh1-Cre |
Transgenic |
E11: otocyst; E18.5: HCs and SCs in cochlea and vestibular organs, spiral and vestibular ganglion neurons |
Cre expression not quantified |
Matei et al. (2005) |
Jax stock #11104 |
CAG-Cre |
Transgenic |
Ubiquitous expression |
Cre expression not quantified |
Sakai and Miyazaki (1997) |
Not commercially available |
Col1A1-Cre |
Transgenic |
Not characterized with a reporter line |
|
Liu et al. (2004) |
MMRRC stock #15398-UCD |
Col2A1-Cre |
Transgenic |
E10.5: non-sensory regions of the otocyst and mesenchymal cells |
Cre expression not quantified |
Ovchinnikov et al. (2000) |
Jax stock #3554 |
Fgf16-Cre |
Knock-in |
E10.5: otic vesicle; P1: semicircular canal cristae, stria vascularis, cochlear spiral prominence epithelium |
Cre expression not quantified |
Hatch et al. (2009) |
Not commercially available |
Foxg1-Cre |
Knock-in |
E8.5: otic placode; E13.5: cochlea, vestibular organs, spiral and vestibular ganglia |
Cre expression not quantified |
Hebert and McConnell (2000) |
Jax stock #4337 |
hGFAP-Cre |
Transgenic |
E13.5: utricle, cristae, non-sensory cells around vestibular organs, postnatal cochlear SCs |
Cre expression not quantified |
Zhuo et al. (2001) |
Jax stock #4600 |
Gfi1-Cre |
Knock-in |
E13.5: vestibular HCs; E15.5: cochlear HCs in basal turn; E18.5: cochlear and vestibular HCs |
Cochlear HCs (93 %), HCs in utricle, saccule, and cristae (90 %) |
Yang et al. (2010b) |
Not commercially available |
Hoxb2-r4-Cre |
Transgenic |
E8.5: otic placode; P0: cochlea, vestibular organs, spiral and vestibular ganglia |
Cre expression not quantified |
Szeto et al. (2009) |
Not commercially available |
Otog-Cre |
Transgenic |
Not characterized with a reporter line |
|
Cohen-Salmon et al. (2002) |
Not commercially available |
Pax2-Cre |
BAC transgenic |
E8.5: otic placode; P0: cochlea, vestibular organs, spiral and vestibular ganglia |
Cre expression not quantified |
Ohyama and Groves (2004) |
MMRRC stock #10569-UNC |
Pax3-Cre |
Knock-in |
E9: otic vesicle and developing spiral and vestibular ganglion; E11.5 to E17.5: cochlea, utricle and saccule |
Cre expression not quantified |
Engleka et al. (2005) |
Jax stock #5549 |
Pax8-Cre |
Knock-in |
E8.5: otic placode; E16.5: epithelial components of the inner ear and spiral and vestibular ganglia |
Cre expression not quantified |
Bouchard et al. (2002) |
EMMA stock #EM:00141 |
Pou3f4-Cre |
Transgenic |
E14.5: otic mesenchyme, adult: temporal bone, spiral ligament, spiral limbus, tympanic border cells, Reissner’s membrane, mesenchymal cells, non-sensory cells in utricle |
Cre expression not quantified |
Ahn et al. (2009) |
Not commercially available |
Pou4f3-Cre |
Transgenic |
E12.5: utricle sensory epithelium; E13.5: zone of non-proliferating cells in cochlea; P6: cochlear HCs and SCs, vestibular HCs and stroma |
Cre expression not quantified |
Sage et al. (2006) |
Not commercially available |
Prestin-Cre |
BAC transgenic |
P6: cochlear and vestibular HCs, spiral ganglia region |
Cre expression not quantified |
Tian et al. (2004) |
Not commercially available |
Prestin-Cre |
Transgenic |
P14: cochlear inner HCs, vestibular HCs, spiral ganglia region; P50: last row of cochlear outer HCs |
Cre expression not quantified |
Li et al. (2004) |
Not commercially available |
Prox1-eGFP/Cre |
Knock-in |
P23: cochlear HCs, pillar cells, Deiters’ cells, GER and LER |
Outer HCs (30 %), inner HCs (4 %), pillar cells and Deiters’ cells (almost 100 %) |
Liu et al. (2012) |
Not commercially available |
SHH-EGFP/Cre |
Knock-in |
P0: spiral ganglion neurons, peripheral nerve fibers surrounding HCs and SCs |
Spiral ganglion neurons (100 %) |
Harfe et al. (2004) |
Jax stock #5622 |
Sox2-Cre |
Transgenic |
Ubiquitous expression |
Cre expression not quantified |
Hayashi et al. (2002) |
Jax stock #4783 |
Wnt1-Cre |
Transgenic |
E9: otic vesicle, developing spiral and vestibular ganglion; E11.5 to E17.5: cochlea, utricle and saccule |
Cre expression not quantified |
Danielian et al. (1998) |
Jax stock #3829 |