FIG. 1.
T cells derived from nasal polyp tissue exhibit an effector memory phenotype. Immunohistochemical staining of nasal polyp tissue shows significant populations of A CD3+ cells and B CD45RO + cells. C Polyp-derived lymphocytes, gated on the CD3+/CD45RO + population are positive for CD44, CXCR3, CD11a and CD28 and are negative for CD62L and CD25. Gray shaded histograms represent surface marker-specific antibodies, while outline histograms represent isotype controls. Histograms show a representative example of six independent experiments.