Nasal polyp-derived CD8+ T cells show impaired upregulation of CD107a surface expression. A At baseline, there are few unstimulated CD8+ T cells from both normal donor PBL and nasal polyp tissue expressing CD107a (2.48% versus 2.06%). Following a 6-h activation with anti-CD3/CD28, CD8+ T cells from nasal polyp tissue show decreased CD107a expression (8.9%, n = 4) compared with CD8+ T cells from normal donor PBL (31.2%, n = 4, p < 0.01). B Representative of four experiments of CD107a expression in CD8+ T cells from normal donor PBL versus nasal polyp cell suspension.