Table 3.
Clinical characteristics for PNS and non-PNS patients.
| Clinical characteristics | PNS (n = 16) | non-PNS (n = 48) | Statistic | p |
|---|---|---|---|---|
| NEGATIVE SYMPTOMS TOTAL (SANS) | ||||
| First assessment | 31.2 ± 13.6 | 27.2 ± 12.4 | t = −1.09 | 0.280 |
| 6-Month | 30.1 ± 11.3 | 17.3 ± 12.0 | t = −3.75 | <0.001 |
| 12-Montha | 30.1 ± 15.4 | 14.8 ± 10.0 | t = −4.14 | <0.001 |
| POSITIVE SYMPTOM TOTAL (SAPS) | ||||
| First assessmenta | 34.5 ± 10.7 | 34.6 ± 17.7 | t = −0.39 | 0.701 |
| 6-Montha | 10.9 ± 9.2 | 9.5 ± 11.7 | t = −1.39 | 0.173 |
| 12-Montha | 16.4 ± 13.9 | 8.6 ± 11.7 | t = −2.73 | 0.011 |
| DEPRESSIVE SYMPTOM TOTAL (CDSS) | ||||
| First assessmenta | 3.7 ± 4.4 | 4.8 ± 5.2 | t = 0.46 | 0.645 |
| 6-Montha | 2.9 ± 3.5 | 1.7 ± 3.2 | t = −1.62 | 0.111 |
| 12-Montha | 1.6 ± 2.3 | 1.8 ± 3.2 | t = 0.16 | 0.873 |
| ANTIPSYCHOTIC DOSAGE (mg/DAY)b | ||||
| First assessmenta | 151.5 ± 116.1 | 173.0 ± 158.8 | t = 0.12 | 0.908 |
| 6-Montha | 174.8 ± 155.3 | 189.3 ± 151.2 | t = 0.33 | 0.746 |
| 12-Montha | 107.8 ± 61.4 | 203.5 ± 248.4 | t = 1.36 | 0.178 |
| MEDICATION ADHERENCEc | ||||
| First assessment | 3.3 ± 1.5 | 3.2 ± 1.5 | U = 362.0 | 0.645 |
| 6-Month | 3.1 ± 1.2 | 3.0 ± 1.4 | U = 379.5 | 0.939 |
| 12-Month | 2.3 ± 1.9 | 3.2 ± 1.5 | U = 294.0 | 0.102 |
| Duration of untreated illness (weeks) | 409.6 ± 283.5 | 281.8 ± 250.7 | t = −1.76 | 0.083 |
| Duration of untreated psychosis (weeks) | 37.2 ± 51.6 | 62.4 ± 84.4 | t = 0.75 | 0.457 |
PNS, persistent negative symptoms.
aAnalyzed using transformed data but values are presented in raw form.
bAntipsychotic total presented in chlorpromazine equivalents.
cMedication adherence: 0 = never adherent to 4 = fully adherent.