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Comparison of various time discretization schemes. (A) Average whole-cell Ca concentrations for four different time discretization schemes [see (C) for details of schemes]. (B) Corresponding voltage traces. (C) Errors and simulation speeds for each of the time discretization schemes. Note: double precision is necessary when using a time step equal to 0.0001 ms, which slows the simulation time by 20% when compared to single precision.
