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. 2012 May 8;3:114. doi: 10.3389/fphys.2012.00114

Table 1.

Parameter values for diffusion and buffering equations.

Symbol Definition Value
Dm Diffusion coefficient of Ca in myoplasm 0.3 μm2 ms−1
Ds Diffusion coefficient of Ca in SR 0.3 μm2 ms−1
vm Local volume element for myoplasm 0.04 μm3*
vs Local volume element for network SR 0.0016 μm3*
Bsr Concentration of SR-bound buffer (myoplasm) 7.0 μM
Ksr Dissociation constant of SR-bound buffer (myoplasm) 0.3 μM
Bcd Concentration of calmodulin buffer (myoplasm) 15.0 μM
Kcd Dissociation constant of calmodulin buffer (myoplasm) 13.0 μM
Bsr Concentration of SR-bound buffer (dyadic space) 47.0 μM
Ksr Dissociation constant of SR-bound buffer (dyadic space) 0.6 μM
Bcd Concentration of calmodulin buffer (dyadic space) 24.0 μM
Kcd Dissociation constant of calmodulin buffer (dyadic space) 7.0 μM
Bcal Concentration of calsequestrin buffer (SR) 140.0 μM
Kcal Dissociation constant of calsequestrin buffer (SR) 650 μM
Bcal Concentration of calsequestrin buffer (jSR) 140.0 μM
Kcal Dissociation constant of calsequestrin buffer (jSR) 650 μM

*Dependent upon spatial discretization.

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