Table 1.
Parameter values for diffusion and buffering equations.
Symbol | Definition | Value |
---|---|---|
Dm | Diffusion coefficient of Ca in myoplasm | 0.3 μm2 ms−1 |
Ds | Diffusion coefficient of Ca in SR | 0.3 μm2 ms−1 |
vm | Local volume element for myoplasm | 0.04 μm3* |
vs | Local volume element for network SR | 0.0016 μm3* |
Bsr | Concentration of SR-bound buffer (myoplasm) | 7.0 μM |
Ksr | Dissociation constant of SR-bound buffer (myoplasm) | 0.3 μM |
Bcd | Concentration of calmodulin buffer (myoplasm) | 15.0 μM |
Kcd | Dissociation constant of calmodulin buffer (myoplasm) | 13.0 μM |
Concentration of SR-bound buffer (dyadic space) | 47.0 μM | |
Dissociation constant of SR-bound buffer (dyadic space) | 0.6 μM | |
Concentration of calmodulin buffer (dyadic space) | 24.0 μM | |
Dissociation constant of calmodulin buffer (dyadic space) | 7.0 μM | |
Bcal | Concentration of calsequestrin buffer (SR) | 140.0 μM |
Kcal | Dissociation constant of calsequestrin buffer (SR) | 650 μM |
Concentration of calsequestrin buffer (jSR) | 140.0 μM | |
Dissociation constant of calsequestrin buffer (jSR) | 650 μM |
*Dependent upon spatial discretization.