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. 2012 Apr 22;2012:494579. doi: 10.1155/2012/494579

Figure 1.

Figure 1

Establishment of the fibroblasts cell model of high matrix metalloproteinase 9 (MMP9) expression. The expressions of MMP9 mRNA, protein levels, and protease activity in model group were 6.05-, 4.12-, and 1.62-fold, respectively, greater than those in control group, which suggested that high expression of MMP9 was induced. When the cells were treated with tissue inhibitor of metalloproteinase 1 (TIMP1), the expression of MMP9 mRNA and protein had no statistical differences compared with model group. *P < 0.01 versus control group. Data are mean ± SEM, n = 5.