Figure 1.
Beta-cell mass equilibrium. Beta-cell proliferation, neogenesis, and hypertrophy (enlarged cell size) increase beta-cell mass, while apoptosis and atrophy (reduced cell size) decrease beta-cell mass.
Beta-cell mass equilibrium. Beta-cell proliferation, neogenesis, and hypertrophy (enlarged cell size) increase beta-cell mass, while apoptosis and atrophy (reduced cell size) decrease beta-cell mass.