Table 2.
Summary of prevalence of SIBO in IBS patients by different diagnostic methods.
| Diagnostic method | N. of IBS patients | N. of controls | Percentage of SIBO in IBS subjects | Percentage of SIBO in controls | Reference |
|---|---|---|---|---|---|
| LHBT | 76 | 40 | 44.7% | 40.0% | Park et al. [115] |
| LHBT | 43 | 56 | 65% | 7% | Scarpellini et al. [116] |
| LHBT | 127 | — | 43% | — | Carrara et al. [5] |
| LHBT | 258 | — | 34.5% | — | Mann and Limoges-Gonzales [117] |
| LHBT | 98 | — | 65% | — | Nucera et al. Lombardolll [118] |
| GHBT | 59 | 37 | 23.7% | 2.7% | Sachdeva et al. [119] |
| GHBT | 98 | — | 36% | — | Reddymasu et al. [120] |
| GHBT | 200 | 50 | 24.5% | 6% | Lombardo et al. |
| GHBT | 1921 | — | 31% | — | Ford et al. [121] |
| GHBT | 130 | 70 | 16.1% | 4.2% | Parodi et al. [122] |
| GHBT | 225 | 100 | 11.1% | 1% | Rana et al. [123] |
| GHBT | 204 | — | 46% | — | Majewski et al. [124] |
| GHBT | 96 | — | 45.8% | — | Cuoco and Salvangnini [125] |
| GHBT | 65 | 102 | 31% | 4% | Lupascu et al. [126] |
| GHBT | 129 | 51 | 8.5% | 2% | Ghoshal et al. [58] |
| Hydrogen | 158 | 34 | 32.9% | 17.9% | Grover et al. [127] |
| Breath test and culture of small bowel aspirate | 162 | 26 | 4% | 4% | Posserud et al. [56] |
Abbreviations used: SIBO: small intestinal bacterial overgrowth; IBS: irritable bowel syndrome; LHBT: lactulose hydrogen breath test; GHBT: glucose hydrogen breath test.