Fig 5.

TprC antibodies have opsonic activity. (A) Percentages of rabbit peritoneal macrophages containing internalized treponemes. Results shown are means ± standard errors of the means for three independent experiments. (B) Representative micrographs of macrophages incubated with motile treponemes and the indicated sera. Each image is a composite of bright-field images, nuclei stained with DAPI, and FITC-labeled T. pallidum. (C) Percentages of treponemes recovered following incubation of rabbit peritoneal macrophages for 4 h with the indicated sera. Results shown are means ± standard errors of the means for three independent experiments. P values of <0.05 (Student's t test) were considered significant.