Table 2.
Concentrations of cytokines secreted by peripheral blood mononuclear cells from HCW according to QFT results
| Marker | Median concn (IQR) |
P valuea | |
|---|---|---|---|
| HCW with LTBI (n = 8) | LTBI-negative HCW (n = 17) | ||
| IL-1RA | 8,491 (6,966–9,885) | 5,837 (5,528–6,869) | 0.140 |
| IL-2 | 87 (69–140) | 10 (9–12) | <0.001 |
| IL-2R | 1,751 (1,696–1,817) | 1,714 (1,678–1,751) | 0.242 |
| IL-4 | 271 (267–282) | 263 (261–269) | 0.126 |
| IL-5 | 15 (14–23) | 13 (13–15) | 0.323 |
| IL-6 | 656 (430–800) | 546 (335–937) | 0.852 |
| IL-7 | 133 (133–134) | 133 (131–133) | 0.435 |
| IL-10 | 8 (6–15) | 7 (6–10) | 0.448 |
| IL-12p40/70 | 848 (783–894) | 857 (823–892) | 0.764 |
| IL-13 | 31 (24–56) | 28 (22–31) | 0.263 |
| IL-15 | 205 (200–211) | 50 (39–200) | 0.021 |
| IL-17 | 208 (206–208) | 208 (208–208) | 0.545 |
| TNF-α | 167 (151–195) | 161 (152–220) | 0.815 |
| GM-CSF | 262 (210–266) | 261 (54–263) | 0.300 |
| MIP-1α | 2,436 (1,607–2,728) | 2,193 (1,078–4,506) | 0.966 |
| MIP-1β | 4,037 (2,286–4,869) | 1,658 (768–1,796) | 0.061 |
| IP-10 | 3,903 (3,004–5,080) | 225 (76–668) | 0.004 |
| MIG | 515 (419-684) | 358 (358–361) | 0.003 |
| Eotaxin | 117 (106–130) | 106 (89–145) | 0.618 |
| RANTES | 16,760 (15,483–16,760) | 13,402 (11,651–16,760) | 0.216 |
| MCP-1 | 15,197 (5,395–22,172) | 5,449 (5,131–7,138) | 0.107 |
| IFN-α | 109 (108–110) | 108 (108–109) | 0.181 |
a
Mann-Whitney test comparing the two groups, with a P value of <0.05 considered statistically significant.