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Activation of carboxylic acid growth substrates and TCA cycle in G. metallireducens. (A) Acetate as carbon source; (B) benzoate as carbon source. During growth on benzoate a succinyl-CoA synthetase is required as only maximally one of the three succinyl-CoA formed per benzoyl-CoA oxidized is regenerated by succinyl-CoA:benzoate CoA transferase. BamY, benzoate-CoA ligase; Bct, succinyl-CoA:benzoate CoA transferase (benzoate CoA transferase); Scs, succinyl-CoA synthetase.
