Table 1.

Characteristics of the donor samples included in this study

Donor (yr of diagnosis) and sample date	Sample type	Type of analysis	ARTa	No. of CD4 cells/μl	No. of viral RNA copies/ml	No. of env sequences	Mean env distance ± SD (%)	Maximum env distance (%)	No. of functional env clones
45 (1990)
2/8/2001	Plasma	env SGA, cloning	Naive	727	11,416	71	3.81 ± 1.37	7.39	9
7/30/2001	PBMC	env SGA, cloning	Naive	656	9,858	28	4.87 ± 1.27	7.75	3
7/14/2006	Plasma	env SGA, cloning	Naive	638	9,129	32	3.93 ± 1.59	7.24	8
8/19/2008	PBMC	MAb isolation	Naive	530	8,588	Not applicable	Not applicable	Not applicable	Not applicable
6/2/2009	Plasma	env SGA, cloning	Naive	686	5,153	55	2.83 ± 1.25	6.21	9
1 (1985)
8/16/1995	Plasma	env SGA, cloning	Naive	1,160	14,650	39	1.53 ± 0.95	3.43	8
7/11/2001	Plasma	env SGA, cloning	Naive	568	10,526	25	2.49 ± 1.58	6.61	6
11/8/2006	Plasma	env SGA, cloning	Off	545	19,260	27	2.69 ± 1.25	5.09	7
B7B5 (1983), 6/20/1988	Serum	env SGA, cloning	Naive	Unknown	Unknown	12	5.07 ± 1.86	7.24	12
18 (1991), 4/20/1999	Plasma	env SGA, cloning	Naive	462	24,648	80	2.07 ± 0.79	3.66	13
N26 (1986), 9/27/2007	Plasma	env SGA, cloning	Naive	387	35,912	67	5.44 ± 2.37	9.42	14
N90 (1985), 5/29/2008	Plasma	env SGA, cloning	Naive	912	8,216	37	3.22 ± 1.25	5.34	11

^aAll donors were either ART naïve or off ART at the time that blood specimens were collected.