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. 2001 May 15;98(11):6360–6365. doi: 10.1073/pnas.111583198

Figure 3.

Figure 3

Anti-CD147 mAb inhibits HIV-1 replication. Triplicate cultures of phytohemagglutinin-activated PBMCs were infected by inoculation with replication-competent HIV-1 strains LAV or ADA (A), or SIV carrying either wild-type (SIV) or chimeric (SIV/HIV-CA) CA (B). Fifty μg/ml anti-CD147 mAb (Ancell) or isotype-matched control mAb (PharMingen) was added 30 min before infection and was present throughout the duration of the experiment. Virus replication was assessed by reverse RT in culture supernatants. Results are shown as mean ± SE and are representative of four (A) and two (B) experiments.