Table 3.
Comparison of the 16F6 and KZ52 epitopes on SUDV and EBOV GP1,2, respectively.
Residues at the shared intersection of the two epitopes are colored orange. Residues listed are conserved between SUDV and EBOV, unless specified.
| Residues of SUDV GP1,2 bound by 16F6 | Residues of EBOV GP1,2 bound by KZ52 |
|---|---|
| S32 | |
| P34 | |
| T39 (note: residue 39 is H in EBOV) | |
| N40 | |
| S41 | |
| T42 | V42 |
| L43 | L43 |
| E44 | Q44 |
| V45 | |
| T46 (is S in EBOV) | |
| E47 (is D in EBOV) | |
| Q50 (is K in EBOV) | |
| V52 | |
| A503 (is T in SUDV) | |
| I504 (is N in SUDV) | |
| V505 (is T in SUDV) | |
| N506 (is K in SUDV) | |
| A507 | |
| Q508 (is T in SUDV) | |
| P509 (is G in SUDV) | |
| K510 | |
| C511 | |
| P513 | P513 |
| N514 | |
| H549 | |
| N550 | N550 |
| Q551 | Q551 |
| N552 | D552 |
| A553 | G553 |
| C556 | C556 |
| G557 | |
| Q560 | |
| L561 | |
| E564 |