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. 2012 Apr 16;4(4):581–612. doi: 10.3390/v4040581

Figure 9.

Figure 9

siRNA silencing of FUT1 and KLHDC7B inhibit HCV replication and infectious virus production. Huh 7.5 cells were transfected with control siRNA (white bars), FUT1 (gray bars) or KLHDC7B (black bars) and infected with JFH-1 (MOI = 0.5) for two hours, supplemented with fresh complete DMEM and continuously cultured to 24, 48, and 72 hours. At each time point, HCV RNA was measured by real-time PCR (A) and the titer of infectious HCV was measured by serial dilution of culture supernatants (B). The percent inhibition produced by each siRNA is shown above each bar in the graph.