Table 1.
LANA-interacting proteins identified in a protein array screen
| Protein | Full name | Functional annotations for proteins identified in protein array screen by categorya |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Replication (n = 10 proteins) | DNA damage/repair (n = 13 proteins) | Transcription regulation (n = 24 proteins) | Signal transduction (n = 13 proteins) | Cell cycle (n = 6 proteins) | Antiviral (n = 2 proteins) | Metabolism (n = 2 proteins) | Ribosome/mRNA processing (n = 12 proteins) | ||
| APEX1 | APEX nuclease 1 | ||||||||
| ASPSCR1 | Alveolar soft part sarcoma chromosome region, candidate 1 | ||||||||
| CDK2AP1 | Cyclin-dependent kinase 2-associated protein 1 | ||||||||
| CENTB2 | ArfGAP with coiled-coil, ankyrin repeat, and PH domains 2 | ||||||||
| CIAO1 | Cytosolic iron-sulfur protein assembly 1 | ||||||||
| CREM | cAMP-responsive element modulator | ||||||||
| ERI1/THEX1 | Exoribonuclease 1 | ||||||||
| FHL1 | Four-and-a-half LIM domains 1 | ||||||||
| GSPT1 | G-to-S phase transition 1 | ||||||||
| GTF3C2 | General transcription factor IIIC | ||||||||
| H3 | Histone 3 | ||||||||
| H4 | Histone 4 | ||||||||
| HCFC2 | Host cell factor C2 | ||||||||
| HMGA1 | High-mobility group AT-hook 1 | ||||||||
| HNRPK | Heterogeneous nuclear ribonucleoprotein K | ||||||||
| HNRPUL1 | Heterogeneous nuclear ribonucleoprotein U-like 1, E1B 55-kDa-associated protein | ||||||||
| HSFY1 | Heat shock transcription factor, Y-linked 1 | ||||||||
| ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | ||||||||
| IL17B | Interleukin 17B | ||||||||
| IRF6 | Interferon regulatory factor 6 | ||||||||
| KAT5 | K(lysine) acetyltransferase 5, TIP60 | ||||||||
| LIG1 | Ligase I, DNA, ATP dependent | ||||||||
| NRF1 | Nuclear respiratory factor 1 | ||||||||
| NUDT21 | Nudix (nucleoside diphosphate-linked moiety X)-type motif 21 | ||||||||
| NXF3 | Nuclear RNA export factor 3 | ||||||||
| OLIG3 | Oligodendrocyte transcription factor 3 | ||||||||
| PCBP2 | Poly(rC) binding protein 2 | ||||||||
| POLB | Polymerase (DNA directed), beta | ||||||||
| PPP2R5E | Protein phosphatase 2, regulatory subunit B′, epsilon isoform | ||||||||
| PPP5C | Protein phosphatase 5, catalytic subunit | ||||||||
| PYGO2 | Pygopus homolog 2 (Drosophila) | ||||||||
| RAD51C | RAD51 homolog C (Saccharomyces cerevisiae) | ||||||||
| RAD51L3 | RAD51-like 3 (S. cerevisiae) | ||||||||
| RBPJ | Recombination signal binding protein for immunoglobulin kappa J region | ||||||||
| REEP2 | Receptor accessory protein 2 | ||||||||
| REEP5 | Receptor accessory protein 5 | ||||||||
| RGS14 | Regulator of G-protein signaling 14 | ||||||||
| RLIM | Ring finger protein, LIM domain interacting | ||||||||
| RPA1 | Replication protein A1, 70 kDa | ||||||||
| RPA2 | Replication protein A2, 32 kDa | ||||||||
| SERBP1 | SERPINE1 mRNA binding protein 1 | ||||||||
| SFRS11 | Serine/arginine-rich splicing factor 11 | ||||||||
| SMARCC2 | SWI/SNF related, matrix associated | ||||||||
| SND1 | Staphylococcal nuclease and tudor domain containing, EBNA2 coactivator p100 | ||||||||
| SNRP70 | Small nuclear ribonucleoprotein, 70 kDa | ||||||||
| SUMO1 | SMT3 suppressor of mif two 3 homolog 1 | ||||||||
| TCEAL6 | Transcription elongation factor A (SII)-like 6 | ||||||||
| TERF1 | Telomeric repeat binding factor 1 | ||||||||
| TFAP2C | Transcription factor AP-2 gamma | ||||||||
| TTF2 | Transcription termination factor, RNA polymerase II | ||||||||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | ||||||||
| XPA | Xeroderma pigmentosum, complementation group A | ||||||||
| ZRANB2 | Zinc finger, RAN-binding domain containing 2 | ||||||||
| DPPA2 | Developmental pluripotency associated 2 | Pluripotency | |||||||
| PPIE | Peptidylprolyl isomerase E (cyclophilin E) | PPIase | |||||||
| C5orf17 | Chromosome 5 open reading frame 17 | Unknown | |||||||
| CCDC25 | Coiled-coil domain containing 25 | Unknown | |||||||
| RBM19 | RNA binding motif protein 19 | Unknown | |||||||
| RELL2 | RELT-like 2 | Unknown | |||||||
| SLC4A1AP | Solute carrier family 4 (anion exchanger), member 1, adaptor protein | Unknown | |||||||
| ZMAT2 | Zinc finger, matrin-type 2 | Unknown | |||||||
a
Functional annotations were generated using the GeneCards Human Gene Database (www.genecards.org). Shading indicates functional annotations.