Table 3.
Viral peptide | Sequence |
---|---|
HCV NS5A-domain I | TEGQCAPKPPTNYKTAIW |
HCV NS5A-LCS-I | ARRLARGSPPSEASSSVS |
HCV NS2 | LRDLAVAVEPIIFSPMEK |
HCV NS5B | KTKLKLTPLPEARLLDLS |
GBV-B NS5A | RTGSLTLPPPPRSVPGVS |
DEN-2 NS5 | SGVDVFFIPPEKCDTLLC |
BVDV 1a NS5 | LFEELLRCPPATKSNKGH |
WNV NS5 | KVDTKAPEPPEGVKYVLN |
Control peptides 18 residues in length that contain single or multiple prolines were not able to bind to CyPA in the spot-binding assay. Sequences were selected from HCV NS5A domain I and low-complexity sequence I, hepatitis C virus (HCV) nonstructural protein 2 (NS2; containing P164), HCV NS5B (containing P540), and the NS5 proteins of GBV-B, dengue virus 2, bovine viral diarrheal virus, and West Nile virus (WNV). Proline residues are highlighted in bold.