Table 1.
Production of COTV progeny in different cell typesa
| Cell line (species) | PFU per cell |
|---|---|
| BSC-40 (Cercopithecus aethiops) | 20 ± 3 |
| C6 (Rattus norvegicus) | 17 ± 1 |
| RK-13 (Oryctolagus cuniculus) | 9 ± 4 |
| L-929 (Mus musculus) | 7 ± 4 |
| Hep-2 (Homo sapiens) | 7 ± 1 |
| MEF (Mus musculus) | 5 ± 4 |
| Vero (Cercopithecus aethiops) | 4 ± 2 |
| CEF (Gallus gallus domesticus) | 2 ± 2 |
| PK-15 (Sus scrofa) | 0 |
| LLC-MK2 (Macaca mulatta) | 0 |
| Rat-2 (Rattus norvegicus) | 0 |
a
Cells were infected with COTV at an MOI of 1 and were collected at 52 h postinfection for virus titration by plaque assay in BSC-40 cells, as described in Materials and Methods. Results are means (± standard deviations) for three assays titrated in duplicate.