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Ultrastructure of type II epithelial cells in SP-C-deficient mice. Lung tissue from adult mice was prepared for electron microscopy. Intact lamellar bodies (intracellular form of surfactant) were detected in SP-C (+/+) type II cells (A) and in SP-C (−/−) type II cells (B), ×10,400. Extracellular tubular myelin forms of surfactant were detected in SP-C (+/+) mice (C) and SP-C (−/−) mice (D), ×26,000.
