Fig 5.

Impact of sarA and nuclease production on susceptibility of UAMS-1 to daptomycin in vivo. Biofilm formation and relative susceptibility to daptomycin were assessed using an in vivo model of catheter-associated biofilm formation (24). Asterisks indicate statistical significance (P < 0.05) by comparison to the results observed with the wild-type strain under the same assay condition. The NS above the bracket indicates the lack of statistical significance between the sarA and sarA nuc12 mutants. Solid dots represent outlying observations.