Capacity for production of the cytokine IL-6 by PBMCs obtained from wild-type (WT) (1892C/C) and heterozygous (HET) (1892C/A) individuals (A) and wild-type individuals (2258G/G), heterozygous (HET) individuals (2258G/A), and individuals homozygous for the mutant-type allele (HOM) (2258A/A) after stimulation for 24 h with P3C, LPS, M. tuberculosis, S. aureus, or E. coli.