Table 3.
Proteins differentially detected after M. avium subsp. hominissuis 109 exposure to macrophages: phagocytosed versus unphagocytosed
| Uniprot accession no. and detection statusa | EMBL annotation | MAV locus tag | No. of unique peptides found according to medium and time point (h) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 7H9 medium |
DMEM |
Extra cellular |
Intra cellular |
|||||||
| 24 | 48 | 24 | 48 | 24 | 48 | 24 | 48 | |||
| Phagocytosed | ||||||||||
| CH601_MYCA1 | 60-kDa chaperonin 1 | MAV_4365 | 4 | 4 | 5 | 3 | 0 | 0 | 1 | 3 |
| CH10_MYCA1 | 10-kDa chaperonin | MAV_4366 | 4 | 4 | 6 | 6 | 0 | 0 | 4 | 4 |
| A0QK66_MYCA1 | Putative uncharacterized protein | MAV_4156 | 1 | 1 | 2 | 2 | 0 | 0 | 1 | 1 |
| A0QLS3_MYCA1 | MarR family protein | MAV_4734 | 4 | 1 | 3 | 2 | 0 | 0 | 2 | 1 |
| Unphagocytosed | ||||||||||
| A0QGW2_MYCA1 | Putative uncharacterized protein | MAV_2964 | 0 | 1 | 1 | 0 | 1 | 2 | 0 | 0 |
| EFG_MYCA1 | Elongation factor G | MAV_4490 | 2 | 0 | 4 | 5 | 2 | 1 | 0 | 0 |
| A0QF13_MYCA1 | Putative ubiquinol-cytochrome c reductase, iron-sulfur subunit | MAV_2297 | 0 | 3 | 0 | 0 | 1 | 1 | 0 | 0 |
a
Phagocytosed means detected in phagocytosed M. avium subsp. hominissuis but not detected in unphagocytosed M. avium subsp. hominissuis. Unphagocytosed means detected in unphagocytosed M. avium subsp. hominissuis but not detected in phagocytosed M. avium subsp. hominissuis.