Table 4.
Cross-referenced list of proteins identified in studies profiling the surface-exposed proteome of M. avium subsp. hominissuis 109, M. avium subsp. paratuberculosis, M. tuberculosis, and M. smegmatisa
| Uniprot annotation | Protein identification |
|||
|---|---|---|---|---|
| M. avium subsp. hominissuis 109 (this study) | M. avium subsp. paratuberculosis (32) | M. tuberculosis (74) | M. smegmatis (74) | |
| 60-kDa chaperonin 2 | MAV_4707 | MAP3936 | Rv3417c | MSMEG_0880 |
| Chaperone protein dnaK | MAV_4808 | MAP3840 | Rv0350 | MSMEG_0709 |
| Elongation factor Tu | MAV_4489 | MAP4143 | NA | MSMEG_1401 |
| Acyl carrier protein | MAV_2913 | MAP1997 | Rv2244 | NA |
| Heparin-binding hemagglutinin | MAV_4675 | MAP3968 | NA | NA |
| Alkylhydroperoxide reductase C | MAV_2839 | MAP1589c | NA | MSMEG_4891 |
| Adenosylhomocysteinase | MAV_4211 | MAP3362c | NA | NA |
| 3-Oxoacyl-[acyl-carrier-protein] synthase 1 | MAV_2192 | MAP1998 | NA | NA |
| 10-kDa chaperonin | MAV_4366 | MAP4264 | NA | NA |
| FadA2 | MAV_4915 | MAP3693 | NA | NA |
| Transcriptional regulator, Crp/Fnr family protein | MAV_0453 | MAP0398c | NA | NA |
| Succinyl-coenzyme A ligase | MAV_1074 | MAP0896 | NA | NA |
| Uncharacterized oxidoreductase | MAV_3816 | MAP3007 | NA | NA |
| Glyceraldehyde-3-phosphate dehydrogenase | MAV_3341 | MAP1164 | NA | MSMEG_3084 |
| Wag31 | MAV_2345 | MAP1889c | NA | NA |
| DNA-directed RNA polymerase subunit alpha | MAV_4398 | MAP4233 | NA | NA |
| Electron transfer protein, beta subunit | MAV_3876 | MAP3061c | NA | MSMEG_2351 |
| Unknown protein | MAV_3813 | MAP3005c | NA | NA |
| Peroxisomal multifunctional enzyme | MAV_5146 | MAP3567 | NA | NA |
| ATP synthase alpha chain | MAV_1525 | MAP2453c | Rv1308 | NA |
| ATP synthase beta chain | MAV_1527 | NA | Rv1310 | NA |
| ATP synthase gamma chain | MAV_1526 | NA | Rv1309 | NA |
| ATP synthase delta chain | MAV_1524 | NA | Rv1307 | NA |
| Aconitate hydratase 1 | MAV_3303 | NA | Rv1475c | MSMEG_3143 |
| Unknown protein | MAV_3615 | NA | Rv2721c | NA |
| MetE | MAV_1262 | NA | Rv1133c | NA |
| Oxidoreductase | MAV_4916 | NA | Rv0242c | NA |
| Catalase-peroxidase | MAV_2753 | NA | Rv1908c | NA |
| Glutamine synthase | MAV_2267 | NA | NA | MSMEG_4290 |
| Succinyl-CoA ligase | MAV_1075 | NA | NA | MSMEG_5524 |
| Universal stress protein | MAV_3137 | NA | NA | MSMEG_3811 |
| Ketol-acid reductoisomerase | MAV_3850 | NA | NA | MSMEG_2374 |
| 60 kDa chaperonin 1 | MAV_4365 | NA | NA | MSMEG_1583 |
| Ribosomal protein S8 | MAV_4451 | NA | NA | MSMEG_1469 |
| 50S ribosomal protein L7/L12 | MAV_4507 | NA | NA | MSMEG_1365 |
| Putative uncharacterized protein | MAV_2412 | NA | Rv2091c | NA |
| MihF protein | Negative control | MAP1122 | NA | MSMEG_3050 |
| DNA binding protein HU | Negative control | MAP3024c | NA | NA |
| 30S Ribosomal protein 3 | Negative control | MAP4167 | NA | NA |
| Malate synthase G | Negative control | NA | Rv1837c | NA |
| Ribosomal protein L18 | Negative control | NA | NA | MSMEG_1471 |
| Enolase | NA | MAP0990 | NA | NA |
| FadE3 | NA | MAP3651c | NA | NA |
| PPE protein PPE26 | NA | MAP1506 | NA | NA |
| PPE protein PPE30 | NA | MAP1519 | NA | NA |
| DesA2 | NA | MAP2698c | NA | NA |
| Unknown protein | NA | MAP1563c | NA | NA |
| PPE protein PPE61 | NA | MAP3532 | NA | NA |
| SerA | NA | MAP3033c | NA | NA |
| FadE24 | NA | MAP3188 | NA | NA |
| Alkylhydroperoxide reductase D | NA | MAP1588c | NA | NA |
| FadE18 | NA | MAP2228 | NA | NA |
| ATP-dependent Clp protease proteolytic subunit | NA | MAP2280c | NA | NA |
| WXG100 protein EsxP | NA | MAP1508 | NA | NA |
| Proline-rich protein | NA | NA | Rv1078 | NA |
| Conserved membrane protein | NA | NA | Rv0227c | NA |
| Serine protease HtrA | NA | NA | Rv1223 | NA |
| Unknown protein | NA | NA | Rv1006 | NA |
| Band protein | NA | NA | Rv1488 | NA |
| FabE10 | NA | NA | Rv0873 | NA |
| Unknown protein | NA | NA | Rv1836c | NA |
| Conserved 35-kDa alanine-rich protein | NA | NA | Rv2744c | NA |
| Trans-acting enoyl reductase | NA | NA | Rv2953 | NA |
| Unknown protein | NA | NA | Rv0831c | NA |
| Hypothetical protease | NA | NA | Rv2224c | NA |
| Glycerol kinase | NA | NA | NA | MSMEG_6759 |
| Fatty acid synthase | NA | NA | NA | MSMEG_4757 |
| Methoxy mycolic acid synthase | NA | NA | NA | MSMEG_0913 |
| Isocitrate dehydrogenase, NADP dependent | NA | NA | NA | MMEG_1654 |
| Unknown protein | NA | NA | NA | MSMEG_6431 |
| Ribosomal protein S1 | NA | NA | NA | MSMEG_3833 |
| Ribonucleoside-diphosphate reductase, alpha subunit | NA | NA | NA | MSMEG_1019 |
| Pyruvate dehydrogenase E1 | NA | NA | NA | MSMEG_4323 |
| Citrate synthase I | NA | NA | NA | MSMEG_5672 |
a
NA, not applicable.