Figure 2.

The nonselective ADO receptor antagonist, 8-SPT (10⁻⁴ M), blocks the ADO-induced decrease in $P_{\mathrm{s}}^{\mathrm{PSA}}$ of porcine coronary arterioles. Means ± SE of ratio of P_s in response to ADO in the presence of 8-SPT (basal) or ADO is over doses from 10⁻⁹ to 10⁻⁵ M relative to the absence of either compound (n = 5–10 for ADO in the presence of 10⁻⁴ M 8-SPT).