Table 4.
Shared genes of M. tuberculosis persistence state. Genes of EHR regulon are in bold
ORF | Gene | Non-replicating state of Wayne (Voskuil et al., 2004) | Gradual depletion of carbon source (Hampshire et al., 2004) | Persistence within macrophages (Schnappinger et al., 2003) | Artificial granuloma in mice (Karakousis et al., 2004). | NC state in the stationary phase (this study) |
Rv0188 | 0.8 | 67.2 | 2.8 | 2.7 | 2.5 | |
Rv0211 | pckA | - | 1.7 | 3.6 | 2.6 | 1.64 |
Rv0251c | hsp | 4.5 | 18.6 | 25.6 | 3.9 | 4.5 |
Rv1894c | 2.0 | 5.1 | 1.8 | - | 2.8 | |
Rv1909c | furA | - | 5.4 | 2.2 | 2.8 | 2.7 |
Rv2011c | 2.1 | 9.5 | 2.5 | - | 2.8 | |
Rv2497c | pdhA | 3.4 | 8.4 | 2.1 | 2.0 | 4.0 |
Rv2660c | 1.5 | 4.3 | 2.1 | 3.3 | 19.7 | |
Rv2662 | 1.5 | 1.5 | 2.0 | - | 12. 9 | |
Rv2710 | sigB | - | 34.6 | 3.8 | 4.7 | 4.6 |
Rv2780 | ald | 6.1 | 2.6 | 2.4 | 2.4 | 4.9 |
Rv3139 | fadE24 | - | 2.2 | 2.0 | 5.8 | 2.4 |
Rv3290c | lat | 3.6 | 25.9 | 7.5 | 5.6 | 4.0 |