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. 2010 Jul;2(2):71–77.

Table 2.

Evaluation of immunogenicity and protectivity of the candidate vaccine based on the M2e peptide of the swine influenza virus.

Group of mice Number of mice First immunization Second immunization Third immunization Influenza virus challenge
A/Duck/Potsdam/1402-6/1986 (Н5N2) A/California/04/2009 (H1N1) A/PR/8/34
Experimental (М2sНВс) 60 60 mice with TiterMax Gold Adjuvant 50 μg/mice s.c. (1) 60 mice with Freund's incomplete adjuvant 50 μg/mice s.c. 60 mice with Freund's incomplete adjuvant 50 μg/mice s.c. 20 mice 5 LD/50 20 mice 5 LD/50 10 mice 5 LD/50
Control 40 PBS PBS PBS 15 mice 5 LD/50 15 mice 5 LD/50 10 mice 5 LD/50

subcutaneous injection