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Main amino acid residues in the active site of PA from E. coli (structure PDB 1AI4). Catalytic βSer1 residue and residue βGln23 are shown in red and orange, respectively. Residues from oxyanion hole are presented in magenta. Residues from substrate-binding domain are shown in green and yellow for subdomains S1 and S2, respectively. Residue αPhe146 belonging to both subdomains is in blue.
