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Pharmacokinetic parameters of raltegravir determined for rats/dogs/rhesus macaques [48]
| Form | AUC, µM·h | Cmax, µM | T1/2, h | F, % | Clp, ml/min/kg | PPB, % |
| OH | 1.0/21/1.8 | 1.2/8/0.3 | ND*/ND/7 | 37/45/8 | 39/6/18 | 74/71/85 |
| Na+ | 1.4/ND/ND | 1.0/ND/ND | ND/ND/ND | ND/ND/ND | ND | ND |
| K+ | 1.3/45/ND | 1.6/24/ND | 73/13/ND | 45/69/ND | ND | ND |
* ND – no data available.
