Table 3.

Distribution of allele frequencies of microsatellite markers D13S141, D13S175, and D13S143 in patients with NSHL (chromosomes with the c.35delG mutation) and in the control sample (normal chromosomes)

Allele (b.p.)	Chromosomes with c.35delG mutation (N=112)		Normal chromosomes(N=358)		χ2	Р(95% significance level)
	Number of chromosomes	Allele frequency	Number of chromosomes	Allele frequency
D13S141
113	0	0	10	0.027±0.008	0.3131	0.6
123	26	0.232±0.031	211	0.589±0.026	43.458	0.000
125	84	0.750±0.042	112	0.312±0.024	67.058	0.000
127	2	0.017±0.002	25	0.069±0.013	4.2629	0.045
D13S175
101	3	0.026±0.012	21	0.058±0.01	1.793	0.300
103	8	0.071±0.021	88	0.245±0.02	15.875	0.000
105	91	0.812±0.036	157	0.438±0.02	47.866	0.000
107	1	0.008±0.007	30	0.083±0.01	7.763	0.005
109	6	0.053±0.024	38	0.106±0.01	2.783	0.100
111	0	0	7	0.019±0.007	2.222	0.150
113	3	0.026±0.01	17	0.047±0.01	0.897	0.064
D13S143
126	1	0.008±0.007	0	0	3.192	0.04
128	1	0.008±0.007	5	0.013±0.006	0.169	0.65
130	90	0.80±0.048	283	0.79±0.021	0.088	0.81
132	6	0.05±0.026	26	0.07±0.013	0.490	0.54
134	12	0.11±0.016	37	0.10±0.013	0.012	0.89
136	2	0.017±0.021	3	0.008±0.004	0.727	0.55
138	0	0	4	0.011±0.005	3.278	0.05