Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Oxidative reactions carried out by Tet proteins. Tet family proteins oxidize 5mC into 5hmC (and to 5fC and 5caC at low levels) in the presence of 2-OG and iron. 5mC and 5hmC can be further oxidized mainly to 5caC by Tet proteins if the reaction system is supplemented with ATP. 5mC, 5-methylcytosine; 5hmC, 5-hydroxymethylcytosine; 5fC, 5-formylcytosine; 5caC, 5-carboxylcytosine.
