Table 1.
Effects of CUS and riluzole on percentage of 13C enrichment
Treatment | Glu-C4 | Gln-C4 | GABA-C2 |
---|---|---|---|
CTR+Saline | 4.0 ± 0.2 | 13.2 ± 0.2 | 2.6 ± 0.2 |
CTR+Riluzole | 3.8 ± 0.1 | 12.8 ± 0.1 | 2.7 ± 0.1 |
CUS+Saline | 3.4 ± 0.1* | 11.5 ± 0.1** | 2.0 ± 0.1* |
CUS+Riluzole | 4.0 ± 0.2# | 12.6 ± 0.2## | 2.8 ± 0.2## |
Table summarizing the effect of CUS and riluzole on the percentage 13C enrichment of Glu-C4, Gln-C4 and GABA-C2. CUS decreased the percentage of 13C enrichment of Glu-C4 (F1,28 = 3.4, P < 0.05), Gln-C4 (F1,28 = 12.12, P < 0.01) and GABA-C2 (F1,28 = 4.93, P < 0.05). Riluzole significantly reversed the effect of CUS on the percentage of 13C enrichment of Glu-C4 (F1,28 = 7.78, P < 0.05), Gln-C4 (F1,28 = 12.51, P < 0.01) and GABA-C2 (F1,28 = 7.696, P < 0.01).
Error bars represent s.e.m.
P < 0.05,
P < 0.01 compared to CTR
P < 0.05,
P < 0.01 compared to CUS, two-way ANOVA, Student–Newman–Keuls post hoc analysis.