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. Author manuscript; available in PMC: 2012 May 8.
Published in final edited form as: Mol Psychiatry. 2008 Sep 30;15(5):501–511. doi: 10.1038/mp.2008.106

Table 1.

Effects of CUS and riluzole on percentage of 13C enrichment

Treatment Glu-C4 Gln-C4 GABA-C2
CTR+Saline 4.0 ± 0.2 13.2 ± 0.2 2.6 ± 0.2
CTR+Riluzole 3.8 ± 0.1 12.8 ± 0.1 2.7 ± 0.1
CUS+Saline 3.4 ± 0.1* 11.5 ± 0.1** 2.0 ± 0.1*
CUS+Riluzole 4.0 ± 0.2# 12.6 ± 0.2## 2.8 ± 0.2##

Table summarizing the effect of CUS and riluzole on the percentage 13C enrichment of Glu-C4, Gln-C4 and GABA-C2. CUS decreased the percentage of 13C enrichment of Glu-C4 (F1,28 = 3.4, P < 0.05), Gln-C4 (F1,28 = 12.12, P < 0.01) and GABA-C2 (F1,28 = 4.93, P < 0.05). Riluzole significantly reversed the effect of CUS on the percentage of 13C enrichment of Glu-C4 (F1,28 = 7.78, P < 0.05), Gln-C4 (F1,28 = 12.51, P < 0.01) and GABA-C2 (F1,28 = 7.696, P < 0.01).

Error bars represent s.e.m.

*

P < 0.05,

**

P < 0.01 compared to CTR

#

P < 0.05,

##

P < 0.01 compared to CUS, two-way ANOVA, Student–Newman–Keuls post hoc analysis.