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. Author manuscript; available in PMC: 2012 Jul 27.
Published in final edited form as: Science. 2012 Jan 5;335(6067):461–463. doi: 10.1126/science.1214457

Figure 2.

Figure 2

Planarian homologs of human centrosome components are required for centriole assembly in multiciliated cells. Left: conservation of centrosome components in animals (red). Ancestral eukaryotic genes are in orange. Green box: centrosome signature genes lost in the planarian Schmidtea mediterranea and the parasite flatworm Schistosoma mansoni but present in Drosophila. Middle: regeneration and locomotion phenotypes in planarians (+: no defect; Abn: abnormal; Inch: inchworming; Dir: abnormal direction of locomotion). Right: +: genes implicated in centriole duplication or ciliogenesis in other systems (red +: this study; S.O.M.).