Table 2.

Drugs implicated in torsades de pointes.

(1) Antiarrhythmic medications

Class IA (Quinidine, Procainamide, and Disopyramide)

Class III (Dofetilide, Ibutilide, Sotalol, and Amiodarone)

Class IV (Verapamil)

(2) Promotility medications

Cisapride

(3) Antimicrobial medications

Macrolides

Erythromycin

Clarithromycin

Fluoroquinolones

Antiprotozoals

Pentamidine

Antimalarials

Chloroquine

(4) Antipsychotic medications

Phenothiazine neuroleptics

Thioridazine

Chlorpromazine

Butyrophenone neuroleptics

Haloperidol

(5) Miscellaneous medications

Arsenic trioxide

Methadone