Figure 1. The Drosophila wing model of axon injury and degeneration.

(A) The nerve tract along the wing margin (L1 and costal veins) is highlighted by mGFP using a dpr-GAL4 driver. A higher magnification of the red box area is shown in (B). Arrowheads, axons; arrow, dendrites; asterisk, the last cluster of L1 neurons. (C–D) On D10 after wing cut, axonal mGFP was undetectable in the wing arch (C) and the thoracic ganglion (D) of wildtype (WT) flies but still robust in Wld^s flies. Scale bar: 100 µm in (A) and (C), 10 µm in (B), and 50 µm in (D).