Table 4.

Serum cytokine concentrations in 41 women with perimenopausal depression, subdivided into those receiving (n = 19) or not (n = 22) selective serotonin reuptake inhibitors (SSRIs) compared to those women without perimenopausal depression (n = 24)

Cytokine	Perimenopausal women with depression		Perimenopausal women without depression, N = 24	P value, Kruskal-Wallis
	Not treated with SSRIs, N = 22	Treated with SSRIs, N = 19
TNFα	9.84 (2.3 to 21.90)	6.31 (4.08 to 9.23)	6.66 (3.01 to 16.50)	0.215, NS
IL-6	1.75 (1.13 to 2.95)	2.47 (1.59 to 4.67)	0.00 (0.00 to 5.63)	0.364, NS
IL-10	5.69 (3.39 to 12.00)	3.91 (1.08 to 10.20)	5.46 (1.31 to 12.90)	0.942, NS

The results of cytokines are expressed as medians (10% to 90%). Unit of serum cytokine concentration is pg/ml.

IL = interleukin; NS = not significant; TNF = tumor necrosis factor.