Figure 3. Venn diagram for 3-way comparison between the proteins of this study, proteins from the trophozoite proteome and the EST data on trophozoite.

Overlaps between the E. histolytica cyst proteomic data (N = 417), trophozoite proteomic data (N = 1825), and the trophozoite specific EST data (N = 1223) were checked. A total of 191 proteins overlapped between the cyst proteomic and trophozoite proteomic datasets. A total of 109 proteins overlapped between the cyst proteomic and the trophozoite EST datasets. Seventy eight proteins overlapped between all three datasets. A total of 195 proteins of cyst proteomic study did not show any overlaps with other two datasets derived from trophozoites of E. histolytica, suggesting these are E. histolytica cyst-specific proteins.