Figure 4. Categories of all 417 proteins detected in 5 cyst samples.

E. histolytica proteins that were present in 1 or more cyst preparations fell into functional categories based on their annotations in the database. Out of 417 proteins, 117 did not have known function and are designated as hypothetical proteins. Four E. histolytica cyst-wall specific proteins (such as Jacob, two chitinases and chitin synthetase) were present in 1 or more cyst preparations. A total of 133 various enzymes (mostly protein kinases and GTPases) were also detected. Among other proteins, 18 transcription or translation related proteins (important for understanding of encystation biology), 12 surface associated proteins, 15 ribosomal proteins, 10 protein-protein interacting proteins, 12 vesicle coating or trafficking protein, 10 calcium signal related proteins, and 6 DNA repair proteins are notable.