Table 1. E. histolytica cyst proteins that show 80% or less identity with E. dispar proteins.
E. histolytica Locus ID | *Detected in samples | Annotation | Transcriptome data** | E. dispar homolog | |||
p-value | fold change: cyst/troph | HM-1 expr | Locus ID | % identity | |||
416.m00035 | 2 | reverse transcriptase, putative | NF | NF | NF | None | N/A |
453.m00043 | 2 | reverse transcriptase, putative | NF | NF | NF | None | N/A |
112.m00115 | 2, 4 | hypothetical protein | NF | NF | NF | None | N/A |
EHI_117680 | 3 | protein kinase, putative | 0.1170 | 2.9 | 0.05 | EDI_160040 | 34 |
EHI_087690 | 3 | hypothetical protein | 0.0282 | 140.8 | 0.05 | EDI_102140 | 44 |
EHI_075310 | 1, 2 | hypothetical protein | 0.2720 | 382.5 | 0.04 | EDI_204760 | 47 |
EHI_182030 | 2 | EhRabF2 | 0.1280 | −1.7 | 1.96 | EDI_154730 | 48 |
EHI_133790 | 1, 2 | hypothetical protein | 0.0161 | 84.9 | 0.04 | EDI_063010 | 49 |
EHI_066720 | 4 | MAEBL, putative | 0.3900 | −1.6 | 2.27 | EDI_281920 | 54 |
EHI_019630 | 1, 4, 5 | hypothetical protein | 0.0001 | 515.8 | 0.08 | EDI_199570 | 54 |
EHI_174540 | 5 | Tyrosyl-DNA phosphodiesterase, putative | 0.5250 | 1.6 | 0.04 | EDI_259130 | 59 |
EHI_113200 | 1 | hypothetical protein | 0.3480 | 2.5 | 0.04 | EDI_078590 | 59 |
EHI_047820 | 2 | BspA-like leucine rich repeat protein, putative | 0.2670 | 1.8 | 0.05 | EDI_238280 | 63 |
EHI_104230 | 1 | hypothetical protein | 0.0001 | 1012.0 | 0.05 | EDI_083080 | 64 |
EHI_146120 | 1, 2, 4 | hypothetical protein | 0.0001 | 59.1 | 0.04 | EDI_105270 | 65 |
EHI_133780 | 1 | hypothetical protein | 0.0001 | 1012.0 | 0.05 | EDI_083080 | 66 |
EHI_158620 | 1 | Opioid growth factor receptor (OGFr) conserved region | 0.3260 | 1.7 | 0.26 | EDI_036800 | 69 |
EHI_059040 | 3 | protein kinase domain containing protein | NF | NF | NF | EDI_142140 | 70 |
EHI_126120 | 1, 2 | DNA mismatch repair protein mutL | 0.4520 | 1.7 | 0.06 | EDI_012590 | 72 |
EHI_034210 | 2 | Protein kinase, putative | 0.0450 | −1.6 | 0.05 | EDI_142140 | 72 |
EHI_174190 | 1, 2 | hypothetical protein | 0.1110 | −3.4 | 0.54 | EDI_018190 | 72 |
EHI_175920 | 4 | protein kinase, putative | NF | NF | NF | EDI_280160 | 74 |
EHI_092210 | 3 | hypothetical protein | 0.1160 | 2.9 | 0.04 | EDI_154030 | 75 |
EHI_163520 | 4 | hypothetical protein 256.t00008 | 0.0563 | −2.5 | 1.60 | EDI_222270 | 80 |
EHI_138010 | 1 | hypothetical protein | 0.3790 | 1.9 | 0.20 | EDI_134120 | 80 |
*: Detected in samples: 1 = 8076; 2 = 4268; 3 = AM951; 4 = AM797; and 5 = CMS33-7132;
**: From [22], 2007; NF = not found; troph = trophozoite; expr = expression; N/A = Not applicable. NB. During the revision of this manuscript, two new trophozoite-specific proteome datasets became available at the AmoebaDB on January 25, 2012. However, none of the proteins listed in Table 1 could be detected in any of the 4 trophozoite-specific proteome datasets available at the AmoebaDB or EST datasets (as of February, 2012).