Figure 4.

Effects of DON on trypanosome-infected mice. Mice were infected with the pleomorphic T. brucei variant clone AnTat 1.1 on day 0, and the number of trypanosomes in the blood was counted (16) every third day, starting at day 4. Two of the mice (■ and ●) were exposed to DON on days 4, 7, 10, and 13. These days are marked with arrows. Two other mice treated with vehicle alone served as controls (⧫ and ▴). The dashed line at the bottom of the graph represents the detection limit.