Fig 1. Effect of TCDD on mouse antral follicle growth in vitro.
Antral follicles were mechanically isolated from young cycling CD1 mice and exposed for 96 hours in culture to TCDD (0.1nM-100nM) or vehicle alone. The follicle diameters were measured every 24 hours for a period of 96 hours. Follicle growth was plotted as percent change in diameter over time from the beginning of the culture. The graph represents the means ±SEM from at least three individual experiments (n=8-16 follicles per treatment group per individual experiment).