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. Author manuscript; available in PMC: 2013 Apr 6.
Published in final edited form as: Cell Immunol. 2012 Apr 6;275(1-2):19–23. doi: 10.1016/j.cellimm.2012.04.001

Fig 4. IL-1 receptor antagonist (IL-1Ra) suppresses IL-17 and IFN-γ production from monocytes stimulated with anti-CD3 and -CD28 antibodies in the presence of AHCC-treated monocytes.

Fig 4

Purified human monocytes that had been treated for 5 hours with AHCC FD (500 μg/ml) were added to autologous memory CD4+ T cells. Cells were then cultured for 7 days with anti-CD3 and -CD28 antibodies. Recombinant human IL-1Ra (125 ng/ml) was added at days 0 and 2 of cell culture. Culture supernatants were collected and analyzed for IL-17 and IFN-γ by ELISA. Bars and error bars indicate mean (n = 7) and standard error of mean, respectively. *P < 0.05.