Figure 2. Renal release of CYP epoxygenase metabolites in response to 10 µg 2-CA.
Release of total EETs + DHTs in response to 10 µg 2-CA was compared in NS- and HS-fed rats in the absence and presence of MS-PPOH. Total EET + DHT release in response to sodium nitroprusside (SNP; 25 ng) in HS-fed rats was also measured. Data are expressed as means ± SE; n = 4–5. *P < 0.05 vs. control (i.e., HS vs. HS + MS-PPOH). #P < 0.05 NS vs. HS.