. Author manuscript; available in PMC: 2013 May 1.

Published in final edited form as: Psychosomatics. 2012 Mar 27;53(3):230–235. doi: 10.1016/j.psym.2011.09.003

Table 1.

Characteristics of subjects with dyskeratosis congenita or DC-like phenotypes.

		Number of Subjects	Median Age in years, (range)	Males: Females	Causative Gene
		Number of Subjects	Median Age in years, (range)	Males: Females	DKC1	TERC	TERT	Unknown^#
DC^*	Adults	7	19 (18–50)	5:2	3	2		2
DC^*	Children	3	15 (9–16)	2:1			2	1
DC-like	Adults	1	31	0:1				1
DC-like	Children	3	16 (13–17)	0:3				3
Overall		14	18.5 (9–50)	8:6	3	2	2	7

One 19 year-old male with DC had the Hoyeraal-Hreidarsson syndrome variant.

Subjects with an unknown causative gene were tested and found to be wild-type for the seven known genes which, when mutated, can cause DC.

Abbreviations: DC, dyskeratosis congenita; DKC1, dyskerin; TERC, RNA component of telomerase; TERT, telomerase