Table 1.
The lipid composition, size, and zeta potential of liposomes.
| Liposomes | Composition (% of mole) |
Size (nm) |
Zeta potential (mV) |
|||||
|---|---|---|---|---|---|---|---|---|
| EPC | Chol | TPP- PEG-PE |
PEG-PE | STPP | PTX* | |||
| TPP-PEG-L- 3% TPP-PEG-L- 5% TPP-PEG-L- 8% |
67 65 62 |
30 30 30 |
3 5 8 |
- - - |
- - - |
- - - |
164.8 ± 45.1 172.0 ± 38.8 163.3 ± 50.9 |
−17 ± 9.4 −13.8 ± 6.2 1.66 ± 5.5 |
| PL- 3% PL- 5% PL- 8% |
67 65 62 |
30 30 30 |
- - - |
3 5 8 |
- - - |
- - - |
169.1 ± 38.9 173.1 ± 22.8 169.3 ± 43.3 |
−21.3 ± 5.9 −20.3 ± 8.9 −20.5 ± 9.2 |
| STPP-L- 1.5% STPP-L- 8% STPP+PEG-L |
68.5 62 54 |
30 30 30 |
- - - |
- - 8 |
1.5 8 8 |
- - - |
164.5 ± 58.8 175.4 ± 56.0 145.3 ± 46.5 |
± ± −4.9 ± 8.2 |
| PL-PTX TPP-PEG-L-PTX |
62 62 |
30 30 |
- 8 |
8 - |
- - |
1 1 |
163.0 ± 37.6 159.8 ± 39.0 |
−18.8 ± 1.3 1.1 ± 0.7 |
*
weight % of total lipid