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Common treatment-related adverse events (pooled data from Study 1 and Study 2; N = 18)
| Adverse event | All grades, n (%) | Grade 3/4, n (%) |
|---|---|---|
| Fatigue | 15 (83) | 5 (28) |
| Anorexia | 13 (72) | 0 |
| Diarrhea | 12 (67) | 0 |
| Hand–foot syndrome | 12 (67) | 1 (6) |
| Hypertension | 11 (61) | 6 (33) |
| Stomatitis | 10 (56) | 0 |
| Hoarseness | 9 (50) | 0 |
| Constipation | 7 (39) | 0 |
| Rash | 6 (33) | 0 |
| Epistaxis | 5 (28) | 0 |
| Nausea | 4 (22) | 0 |
| Headache | 4 (22) | 0 |
