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. Author manuscript; available in PMC: 2013 May 7.
Published in final edited form as: Mol Pharm. 2012 Apr 6;9(5):1384–1395. doi: 10.1021/mp200641e

Figure 3.

Figure 3

Structures of weakly basic drugs shown to cause a significant expansion in lysosomal volume. The predicted pKa and LogP values for each of the drugs are listed (predictions obtained using ChemAxon software available at http://www.chemicalize.org).