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. 2011 Nov 10;67A(6):553–564. doi: 10.1093/gerona/glr197

Figure 2.

Figure 2.

(A) High-fat diet (HFD) impairs glucose tolerance in Lewis dwarf rats. Shown are changes in blood glucose levels after 1 g/kg oral glucose dose in Lewis dwarf rats and control rats fed a HFD or standard diet (SD). (B) Areas under the curves (AUC) were significantly reduced in Lewis dwarf rats fed an SD. HFD significantly increased AUC in Lewis dwarf rats eliminating the difference between the two genotypes. Data are means ± SEM; *p < .05 versus control; #p < .05 versus SD. (C–G) Serum levels of IGF-1 (C), insulin (D), leptin (E), adiponectin (F), and resistin (G). Data are means ± SEM; *p < .05 versus respective control; #p < .05 versus SD (n = 5–7).